Chromosome Folding Promotes Intrachromosomal Aberrations under Radiation- and Nuclease-Induced DNA Breakage

The long-standing question in radiation and cancer biology is how principles of chromosome organization impact the formation of chromosomal aberrations (CAs). To address this issue, we developed a physical modeling approach and analyzed high-throughput genomic data from chromosome conformation captu...

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Detalles Bibliográficos
Autores principales: Eidelman, Yuri, Salnikov, Ilya, Slanina, Svetlana, Andreev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618582/
https://www.ncbi.nlm.nih.gov/pubmed/34830065
http://dx.doi.org/10.3390/ijms222212186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618582/
https://www.ncbi.nlm.nih.gov/pubmed/34830065
http://dx.doi.org/10.3390/ijms222212186

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