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Sublingual Immunization with Chimeric C1q/CD40 Ligand/HIV Virus-like Particles Induces Strong Mucosal Immune Responses against HIV

Development of a vaccine that can elicit robust HIV specific antibody responses in the mucosal compartments is desired for effective prevention of HIV via sexual transmission. However, the current mucosal vaccines have either poor immunogenicity when administered orally or invite safety concerns whe...

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Detalles Bibliográficos
Autores principales: Liu, Dongliang, Zhang, Sheng, Poteet, Ethan, Marin-Muller, Christian, Chen, Changyi, Yao, Qizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618657/
https://www.ncbi.nlm.nih.gov/pubmed/34835167
http://dx.doi.org/10.3390/vaccines9111236