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Modulating the Blood–Brain Barrier: A Comprehensive Review

The highly secure blood–brain barrier (BBB) restricts drug access to the brain, limiting the molecular toolkit for treating central nervous system (CNS) diseases to small, lipophilic drugs. Development of a safe and effective BBB modulator would revolutionise the treatment of CNS diseases and future...

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Detalles Bibliográficos
Autores principales: Whelan, Rory, Hargaden, Grainne C., Knox, Andrew J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618722/
https://www.ncbi.nlm.nih.gov/pubmed/34834395
http://dx.doi.org/10.3390/pharmaceutics13111980