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Promoter Demethylation Upregulates STEAP1 Gene Expression in Human Prostate Cancer: In Vitro and In Silico Analysis

The Six Transmembrane Epithelial Antigen of the Prostate (STEAP1) is an oncogene overexpressed in several human tumors, particularly in prostate cancer (PCa). However, the mechanisms involved in its overexpression remain unknown. It is well known that epigenetic modifications may result in abnormal...

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Detalles Bibliográficos
Autores principales: Rocha, Sandra M., Sousa, Inês, Gomes, Inês M., Arinto, Patrícia, Costa-Pinheiro, Pedro, Coutinho, Eduarda, Santos, Cecília R., Jerónimo, Carmen, Lemos, Manuel C., Passarinha, Luís A., Socorro, Sílvia, Maia, Cláudio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618799/
https://www.ncbi.nlm.nih.gov/pubmed/34833128
http://dx.doi.org/10.3390/life11111251