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Microbial Efflux Pump Inhibitors: A Journey around Quinoline and Indole Derivatives

Antimicrobial resistance (AMR) is a complex threat to human health and, to date, it represents a hot topic in drug discovery. The use of non-antibiotic molecules to block resistance mechanisms is a powerful alternative to the identification of new antibiotics. Bacterial efflux pumps exert the early...

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Detalles Bibliográficos
Autores principales: Cernicchi, Giada, Felicetti, Tommaso, Sabatini, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618814/
https://www.ncbi.nlm.nih.gov/pubmed/34834098
http://dx.doi.org/10.3390/molecules26226996