Regulation of ROS-Dependent JNK Pathway by 2’-Hydroxycinnamaldehyde Inducing Apoptosis in Human Promyelocytic HL-60 Leukemia Cells

The present study demonstrated that 2′-hydroxycinnamaldehyde (2′-HCA) induced apoptosis in human promyelocytic leukemia HL-60 cells through the activation of mitochondrial pathways including (1) translocation of Bim and Bax from the cytosol to mitochondria, (2) downregulation of Bcl-2 protein expres...

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Detalles Bibliográficos
Autores principales: Chung, Kyung-Sook, Yoo, Chae-Bin, Lee, Jeong-Hun, Lee, Hwi-Ho, Park, Sang-Eun, Han, Hee-Soo, Lee, Su-Yeon, Kwon, Byoung-Mok, Choi, Jung-Hye, Lee, Kyung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618870/
https://www.ncbi.nlm.nih.gov/pubmed/34834209
http://dx.doi.org/10.3390/pharmaceutics13111794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618870/
https://www.ncbi.nlm.nih.gov/pubmed/34834209
http://dx.doi.org/10.3390/pharmaceutics13111794

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