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Sclerostin and Its Involvement in the Pathogenesis of Idiopathic Scoliosis

Idiopathic scoliosis is a disorder of unknown etiology. Bone biopsies from idiopathic scoliosis patients revealed changes at cellular and molecular level. Osteocytic sclerostin is downregulated, and serum level of sclerostin is decreased. Osteocytes in idiopathic scoliosis appear to be less active w...

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Detalles Bibliográficos
Autores principales: Vasiliadis, Elias S., Evangelopoulos, Dimitrios Stergios, Kaspiris, Angelos, Vlachos, Christos, Pneumaticos, Spyros G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618875/
https://www.ncbi.nlm.nih.gov/pubmed/34830568
http://dx.doi.org/10.3390/jcm10225286