Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD

Increased lipid bioavailability in a diet favors lipid accumulation, enhancing hepatic lipotoxicity and contributing to insulin resistance (IR) development. The aim of our study was to examine time-dependent alterations in the intrahepatic content of sphingolipids and insulin signaling pathway in ra...

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Detalles Bibliográficos
Autores principales: Sztolsztener, Klaudia, Konstantynowicz-Nowicka, Karolina, Harasim-Symbor, Ewa, Chabowski, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618899/
https://www.ncbi.nlm.nih.gov/pubmed/34830360
http://dx.doi.org/10.3390/ijms222212478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618899/
https://www.ncbi.nlm.nih.gov/pubmed/34830360
http://dx.doi.org/10.3390/ijms222212478

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