Optimization of Personalized Amlodipine Dosing Strategies for Children Based on Pharmacokinetic Data from Chinese Male Adults and PBPK Modeling

For children, a special population who are continuously developing, a reasonable dosing strategy is the key to clinical therapy. Accurate dose predictions can help maximize efficacy and minimize pain in pediatrics. Methods: This study collected amlodipine pharmacokinetics (PK) data from 236 Chinese...

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Detalles Bibliográficos
Autores principales: Han, Xiaolu, Hong, Xiaoxuan, Li, Xianfu, Wang, Yuxi, Wang, Zengming, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618961/
https://www.ncbi.nlm.nih.gov/pubmed/34828663
http://dx.doi.org/10.3390/children8110950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618961/
https://www.ncbi.nlm.nih.gov/pubmed/34828663
http://dx.doi.org/10.3390/children8110950

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