Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms

The wild-type protein p53 plays a key role in preventing the formation of neoplasms by controlling cell growth. However, in more than a half of all cancers, the TP53 gene has missense mutations that appear during tumorigenesis. In most cases, the mutated gene encodes a full-length protein with the s...

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Detalles Bibliográficos
Autores principales: Butturini, Elena, Butera, Giovanna, Pacchiana, Raffaella, Carcereri de Prati, Alessandra, Mariotto, Sofia, Donadelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618966/
https://www.ncbi.nlm.nih.gov/pubmed/34831372
http://dx.doi.org/10.3390/cells10113149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618966/
https://www.ncbi.nlm.nih.gov/pubmed/34831372
http://dx.doi.org/10.3390/cells10113149

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