Investigation of the Transport Pathways Associated with Enhanced Brain Delivery of Peptide Drugs by Intranasal Coadministration with Penetratin

We previously found that coadministering peptides and proteins with the cell-penetrating peptide L-penetratin intranasally significantly increased transport to the brain and enhanced pharmacological effects. The present study aimed to clarify the mechanisms of nose-to-brain drug delivery enhancement...

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Detalles Bibliográficos
Autores principales: Kamei, Noriyasu, Suwabe, Susumu, Arime, Kenji, Bando, Hidemi, Murata, Kaho, Yamaguchi, Maika, Yokoyama, Natsuki, Tanaka, Erina, Hashimoto, Ayaka, Kanazawa, Takanori, Ago, Yukio, Takeda-Morishita, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618983/
https://www.ncbi.nlm.nih.gov/pubmed/34834159
http://dx.doi.org/10.3390/pharmaceutics13111745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618983/
https://www.ncbi.nlm.nih.gov/pubmed/34834159
http://dx.doi.org/10.3390/pharmaceutics13111745

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