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Discovery of New Ginsenol-Like Compounds with High Antiviral Activity

A number of framework amides with a ginsenol backbone have been synthesized using the Ritter reaction. We named the acetamide as Ginsamide. A method was developed for the synthesis of the corresponding amine and thioacetamide. The new compounds revealed a high activity against H1N1 influenza, which...

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Detalles Bibliográficos
Autores principales: Volobueva, Aleksandrina S., Yarovaya, Olga I., Kireeva, Marina V., Borisevich, Sophia S., Kovaleva, Kseniya S., Mainagashev, Iliya Ya., Gatilov, Yuri V., Ilyina, Margarita G., Zarubaev, Vladimir V., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619001/
https://www.ncbi.nlm.nih.gov/pubmed/34833886
http://dx.doi.org/10.3390/molecules26226794