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IRE1-Mediated Unfolded Protein Response Promotes the Replication of Tick-Borne Flaviviruses in a Virus and Cell-Type Dependent Manner

Tick-borne flaviviruses (TBFV) can cause severe neurological complications in humans, but differences in tissue tropism and pathogenicity have been described for individual virus strains. Viral protein synthesis leads to the induction of the unfolded protein response (UPR) within infected cells. The...

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Detalles Bibliográficos
Autores principales: Breitkopf, Veronika J. M., Dobler, Gerhard, Claus, Peter, Naim, Hassan Y., Steffen, Imke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619205/
https://www.ncbi.nlm.nih.gov/pubmed/34834970
http://dx.doi.org/10.3390/v13112164