Repeated MDA5 Gene Loss in Birds: An Evolutionary Perspective

Two key cytosolic receptors belonging to the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family sense the viral RNA-derived danger signals: RIG-I and melanoma differentiation-associated protein 5 (MDA5). Their activation establishes an antiviral state by downstream signaling that ulti...

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Detalles Bibliográficos
Autores principales: Krchlíková, Veronika, Hron, Tomáš, Těšický, Martin, Li, Tao, Hejnar, Jiří, Vinkler, Michal, Elleder, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619217/
https://www.ncbi.nlm.nih.gov/pubmed/34834938
http://dx.doi.org/10.3390/v13112131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619217/
https://www.ncbi.nlm.nih.gov/pubmed/34834938
http://dx.doi.org/10.3390/v13112131

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