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BRAF-Inhibitor-Induced Metabolic Alterations in A375 Melanoma Cells

Acquired drug tolerance has been a major challenge in cancer therapy. Recent evidence has revealed the existence of slow-cycling persister cells that survive drug treatments and give rise to multi-drug-tolerant mutants in cancer. Cells in this dynamic persister state can escape drug treatment by und...

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Detalles Bibliográficos
Autores principales: Karki, Prashant, Sensenbach, Shayne, Angardi, Vahideh, Orman, Mehmet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619236/
https://www.ncbi.nlm.nih.gov/pubmed/34822435
http://dx.doi.org/10.3390/metabo11110777