Knockout of the hsd11b2 Gene Extends the Cortisol Stress Response in Both Zebrafish Larvae and Adults

The Hsd11b2 enzyme converts cortisol into its inactive form, cortisone and regulates cortisol levels, in particular in response to stress. Taking advantage of CRISPR/Cas9 technology, we generated a hsd11b2 zebrafish mutant line to evaluate the involvement of this gene in stress response regulation....

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Detalles Bibliográficos
Autores principales: Theodoridi, Antonia, Dinarello, Alberto, Badenetti, Lorenzo, Pavlidis, Michail, Dalla Valle, Luisa, Tsalafouta, Aleka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619348/
https://www.ncbi.nlm.nih.gov/pubmed/34830405
http://dx.doi.org/10.3390/ijms222212525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619348/
https://www.ncbi.nlm.nih.gov/pubmed/34830405
http://dx.doi.org/10.3390/ijms222212525

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