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Initial Screening of Poly(ethylene glycol) Amino Ligands for Affinity Purification of Plasmid DNA in Aqueous Two-Phase Systems

Gene therapy and DNA vaccination are among the most expected biotechnological and medical advances for the coming years. However, the lack of cost-effective large-scale production and purification of pharmaceutical-grade plasmid DNA (pDNA) still hampers their wide application. Downstream processing,...

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Detalles Bibliográficos
Autores principales: da Silva, Nuno R., Jorge, Paula, Martins, José A., Teixeira, José A., Marcos, João C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619368/
https://www.ncbi.nlm.nih.gov/pubmed/34833014
http://dx.doi.org/10.3390/life11111138