Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection

Primary varicella-zoster virus (VZV) infection leads to varicella and the establishment of lifelong latency in sensory ganglion neurons. Reactivation of latent VZV causes herpes zoster, which is frequently associated with chronic pain. Latent viral gene expression is restricted to the VZV latency-as...

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Detalles Bibliográficos
Autores principales: Braspenning, Shirley E., Lebbink, Robert Jan, Depledge, Daniel P., Schapendonk, Claudia M. E., Anderson, Laura A., Verjans, Georges M. G. M., Sadaoka, Tomohiko, Ouwendijk, Werner J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619377/
https://www.ncbi.nlm.nih.gov/pubmed/34835095
http://dx.doi.org/10.3390/v13112289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619377/
https://www.ncbi.nlm.nih.gov/pubmed/34835095
http://dx.doi.org/10.3390/v13112289

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