The P2Y12 Receptor Antagonist Selatogrel Dissolves Preformed Platelet Thrombi In Vivo

Selatogrel, a potent and reversible antagonist of the P2Y12 receptor, inhibited FeCl(3)-induced thrombosis in rats. Here, we report the anti-thrombotic effect of selatogrel after subcutaneous applications in guinea pigs and mice. Selatogrel inhibited platelet function only 10 min after subcutaneous...

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Detalles Bibliográficos
Autores principales: Crescence, Lydie, Kramberg, Markus, Baumann, Martine, Rey, Markus, Roux, Sebastien, Panicot-Dubois, Laurence, Dubois, Christophe, Riederer, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619398/
https://www.ncbi.nlm.nih.gov/pubmed/34830631
http://dx.doi.org/10.3390/jcm10225349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619398/
https://www.ncbi.nlm.nih.gov/pubmed/34830631
http://dx.doi.org/10.3390/jcm10225349

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