ω-3 DPA Protected Neurons from Neuroinflammation by Balancing Microglia M1/M2 Polarizations through Inhibiting NF-κB/MAPK p38 Signaling and Activating Neuron-BDNF-PI3K/AKT Pathways

Microglia M1 phenotype causes HPA axis hyperactivity, neurotransmitter dysfunction, and production of proinflammatory mediators and oxidants, which may contribute to the etiology of depression and neurodegenerative diseases. Eicosapentaenoic acid (EPA) may counteract neuroinflammation by increasing...

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Detalles Bibliográficos
Autores principales: Liu, Baiping, Zhang, Yongping, Yang, Zhiyou, Liu, Meijun, Zhang, Cai, Zhao, Yuntao, Song, Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619469/
https://www.ncbi.nlm.nih.gov/pubmed/34822458
http://dx.doi.org/10.3390/md19110587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619469/
https://www.ncbi.nlm.nih.gov/pubmed/34822458
http://dx.doi.org/10.3390/md19110587

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