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Characterization of an In Vivo Neutralizing Anti-Vaccinia Virus D8 Single-Chain Fragment Variable (scFv) from a Human Anti-Vaccinia Virus-Specific Recombinant Library

A panel of potent neutralizing antibodies are protective against orthopoxvirus (OPXV) infections. For the development of OPXV-specific recombinant human single-chain antibodies (scFvs), the IgG repertoire of four vaccinated donors was amplified from peripheral B-lymphocytes. The resulting library co...

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Detalles Bibliográficos
Autores principales: Diesterbeck, Ulrike S., Ahsendorf, Henrike P., Frenzel, André, Sharifi, Ahmad Reza, Schirrmann, Thomas, Czerny, Claus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619513/
https://www.ncbi.nlm.nih.gov/pubmed/34835240
http://dx.doi.org/10.3390/vaccines9111308