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IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 Acetylation

IL-6 was found to be overexpressed in the adipose tissue of obese individuals, which may cause insulin resistance. However, the regulation of IL-6 in adipocytes in obesity setting remains to be explored. Since IL-1β and TNFα are increased in obese adipose tissue and promote inflammation, we investig...

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Detalles Bibliográficos
Autores principales: Al-Roub, Areej, Al Madhoun, Ashraf, Akhter, Nadeem, Thomas, Reeby, Miranda, Lavina, Jacob, Texy, Al-Ozairi, Ebaa, Al-Mulla, Fahd, Sindhu, Sardar, Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619559/
https://www.ncbi.nlm.nih.gov/pubmed/34831450
http://dx.doi.org/10.3390/cells10113228