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Detection of 2-Hydroxyglutarate by 3.0-Tesla Magnetic Resonance Spectroscopy in Gliomas with Rare IDH Mutations: Making Sense of “False-Positive” Cases

We have previously published a study on the reliable detection of 2-hydroxyglutarate (2HG) in lower-grade gliomas by magnetic resonance spectroscopy (MRS). In this short article, we re-evaluated five glioma cases originally assessed as isocitrate dehydrogenase (IDH) wildtype, which showed a high acc...

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Detalles Bibliográficos
Autores principales: Natsumeda, Manabu, Igarashi, Hironaka, Gabdulkhaev, Ramil, Takahashi, Haruhiko, Motohashi, Kunio, Ogura, Ryosuke, Watanabe, Jun, Tsukamoto, Yoshihiro, Okamoto, Kouichirou, Kakita, Akiyoshi, Nakada, Tsutomu, Fujii, Yukihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619588/
https://www.ncbi.nlm.nih.gov/pubmed/34829476
http://dx.doi.org/10.3390/diagnostics11112129