One-Pot Multicomponent Synthesis of Methoxybenzo[h]quinoline-3-carbonitrile Derivatives; Anti-Chagas, X-ray, and In Silico ADME/Tox Profiling Studies

Several methoxybenzo[h]quinoline-3-carbonitrile analogs were designed and synthesized in a repositioning approach to developing compounds with anti-prostate cancer and anti-Chagas disease properties. The compounds were synthesized through a sequential multicomponent reaction of aromatic aldehydes, m...

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Detalles Bibliográficos
Autores principales: Ramírez, Hegira, Charris, Katiuska, Fernandez-Moreira, Esteban, Nogueda-Torres, Benjamín, Capparelli, Mario V., Ángel, Jorge, Charris, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619670/
https://www.ncbi.nlm.nih.gov/pubmed/34834070
http://dx.doi.org/10.3390/molecules26226977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619670/
https://www.ncbi.nlm.nih.gov/pubmed/34834070
http://dx.doi.org/10.3390/molecules26226977

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