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Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5

Pulmonary fibrosis is a serious disease characterized by extracellular matrix (ECM) component overproduction and remodeling. Insulin-like growth factor-binding protein 5 (IGFBP5) is a conserved member of the IGFBP family of proteins that is overexpressed in fibrotic tissues and promotes fibrosis. We...

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Detalles Bibliográficos
Autores principales: Nguyen, Xinh-Xinh, Renaud, Ludivine, Feghali-Bostwick, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619832/
https://www.ncbi.nlm.nih.gov/pubmed/34830489
http://dx.doi.org/10.3390/ijms222212609