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Dysfunction of the hypothalamic-pituitary-adrenal axis in male rat offspring with prenatal food restriction: Fetal programming of hypothalamic hyperexcitability and poor hippocampal feedback

Prenatal food restriction (PFR) induces dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis in the adult offspring. The aim of the present study was to identify the underlying mechanism of this process. Pregnant rats were placed on a restricted diet between gestational day 11 and 21. The of...

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Detalles Bibliográficos
Autores principales: Wen, Yinxian, Cheng, Siyuan, Lu, Juan, He, Xia, Jiao, Zhexiao, Xu, Dan, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619836/
https://www.ncbi.nlm.nih.gov/pubmed/34796908
http://dx.doi.org/10.3892/mmr.2021.12537