Impact of Airway Inflammation on the Efficacy of CFTR Modulators

Defective CFTR biogenesis and activity in cystic fibrosis airways leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. Most cystic fibrosis patients have at least one copy of the F508del CFTR mutation, which results in a protein reta...

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Detalles Bibliográficos
Autores principales: Ribeiro, Carla M. P., Gentzsch, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619863/
https://www.ncbi.nlm.nih.gov/pubmed/34831482
http://dx.doi.org/10.3390/cells10113260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619863/
https://www.ncbi.nlm.nih.gov/pubmed/34831482
http://dx.doi.org/10.3390/cells10113260

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