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Downregulation of Cell Surface Major Histocompatibility Complex Class I Expression Is Mediated by the Left-End Transcription Unit of Fowl Adenovirus 9

Major histocompatibility complex class I (MHC-I) molecules play a critical role in the host’s antiviral response by presenting virus-derived antigenic peptides to cytotoxic T lymphocytes (CTLs), enabling the clearance of virus-infected cells. Human adenoviruses evade CTL-mediated cell lysis, in part...

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Detalles Bibliográficos
Autores principales: Griffin, Bryan D., Corredor, Juan Carlos, Pei, Yanlong, Nagy, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619926/
https://www.ncbi.nlm.nih.gov/pubmed/34835017
http://dx.doi.org/10.3390/v13112211