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Intratumoral Heterogeneity Promotes Collective Cancer Invasion through NOTCH1 Variation
Cellular and molecular heterogeneity within tumors has long been associated with the progression of cancer to an aggressive phenotype and a poor prognosis. However, how such intratumoral heterogeneity contributes to the invasiveness of cancer is largely unknown. Here, using a tumor bioengineering ap...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619970/ https://www.ncbi.nlm.nih.gov/pubmed/34831307 http://dx.doi.org/10.3390/cells10113084 |