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Highly Specific Sigma Receptor Ligands Exhibit Anti-Viral Properties in SARS-CoV-2 Infected Cells

(1) Background: There is a strong need for prevention and treatment strategies for COVID-19 that are not impacted by SARS-CoV-2 mutations emerging in variants of concern. After virus infection, host ER resident sigma receptors form direct interactions with non-structural SARS-CoV-2 proteins present...

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Detalles Bibliográficos
Autores principales: Ostrov, David A., Bluhm, Andrew P., Li, Danmeng, Khan, Juveriya Qamar, Rohamare, Megha, Rajamanickam, Karthic, K. Bhanumathy, Kalpana, Lew, Jocelyne, Falzarano, Darryl, Vizeacoumar, Franco J., Wilson, Joyce A., Mottinelli, Marco, Kanumuri, Siva Rama Raju, Sharma, Abhisheak, McCurdy, Christopher R., Norris, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620039/
https://www.ncbi.nlm.nih.gov/pubmed/34832669
http://dx.doi.org/10.3390/pathogens10111514