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Randomized quantile residuals for diagnosing zero-inflated generalized linear mixed models with applications to microbiome count data
BACKGROUND: For differential abundance analysis, zero-inflated generalized linear models, typically zero-inflated NB models, have been increasingly used to model microbiome and other sequencing count data. A common assumption in estimating the false discovery rate is that the p values are uniformly...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620156/ https://www.ncbi.nlm.nih.gov/pubmed/34823466 http://dx.doi.org/10.1186/s12859-021-04371-6 |