Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis

Clathrin-mediated endocytosis (CME) is critical for cellular signal transduction, receptor recycling, and membrane homeostasis in mammalian cells. Acute depletion of cholesterol disrupts CME, motivating analysis of CME dynamics in the context of human disorders of cholesterol metabolism. We report t...

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Detalles Bibliográficos
Autores principales: Anderson, Ruthellen H., Sochacki, Kem A., Vuppula, Harika, Scott, Brandon L., Bailey, Elizabeth M., Schultz, Maycie M., Kerkvliet, Jason G., Taraska, Justin W., Hoppe, Adam D., Francis, Kevin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620193/
https://www.ncbi.nlm.nih.gov/pubmed/34788623
http://dx.doi.org/10.1016/j.celrep.2021.110008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620193/
https://www.ncbi.nlm.nih.gov/pubmed/34788623
http://dx.doi.org/10.1016/j.celrep.2021.110008

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