Inhibition of matrix stiffness relating integrin β1 signaling pathway inhibits tumor growth in vitro and in hepatocellular cancer xenografts

BACKGROUND: Cancer development is strictly correlated to composition and physical properties of the extracellular matrix. Particularly, a higher matrix stiffness has been demonstrated to promote tumor sustained growth. Our purpose was to explore the role of matrix stiffness in liver cancer developme...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Changsong, Jiang, Xiaozhong, Huang, Bin, Zhou, Wenhao, Cui, Xiao, Zheng, Chenghong, Liu, Fenghao, Bi, Jieling, Zhang, Yi, Luo, Hong, Yuan, Lin, Yang, Jianyong, Yu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620230/
https://www.ncbi.nlm.nih.gov/pubmed/34823500
http://dx.doi.org/10.1186/s12885-021-08982-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620230/
https://www.ncbi.nlm.nih.gov/pubmed/34823500
http://dx.doi.org/10.1186/s12885-021-08982-3

Ejemplares similares