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Inhibition of matrix stiffness relating integrin β1 signaling pathway inhibits tumor growth in vitro and in hepatocellular cancer xenografts
BACKGROUND: Cancer development is strictly correlated to composition and physical properties of the extracellular matrix. Particularly, a higher matrix stiffness has been demonstrated to promote tumor sustained growth. Our purpose was to explore the role of matrix stiffness in liver cancer developme...
Autores principales: | Wang, Changsong, Jiang, Xiaozhong, Huang, Bin, Zhou, Wenhao, Cui, Xiao, Zheng, Chenghong, Liu, Fenghao, Bi, Jieling, Zhang, Yi, Luo, Hong, Yuan, Lin, Yang, Jianyong, Yu, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620230/ https://www.ncbi.nlm.nih.gov/pubmed/34823500 http://dx.doi.org/10.1186/s12885-021-08982-3 |
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