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TRPA1-Mediated Src Family Kinases Activity Facilitates Cortical Spreading Depression Susceptibility and Trigeminovascular System Sensitization

Transient receptor potential ankyrin 1 (TRPA1) plays a role in migraine and is proposed as a promising target for migraine therapy. However, TRPA1-induced signaling in migraine pathogenesis is poorly understood. In this study, we explored the hypothesis that Src family kinases (SFKs) transmit TRPA1...

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Detalles Bibliográficos
Autores principales: Nie, Lingdi, Jiang, Liwen, Quinn, John P., Grubb, Blair D., Wang, Minyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620265/
https://www.ncbi.nlm.nih.gov/pubmed/34830154
http://dx.doi.org/10.3390/ijms222212273