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The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation

Basal cells (BCs) are stem/progenitor cells of the mucociliary airway epithelium, and their differentiation is orchestrated by the NOTCH signaling pathway. NOTCH3 receptor signaling regulates BC to club cell differentiation; however, the downstream responses that regulate this process are unknown. O...

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Detalles Bibliográficos
Autores principales: Bodas, Manish, Subramaniyan, Bharathiraja, Moore, Andrew R., Metcalf, Jordan P., Ocañas, Sarah R., Freeman, Willard M., Georgescu, Constantin, Wren, Jonathan D., Walters, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620267/
https://www.ncbi.nlm.nih.gov/pubmed/34831437
http://dx.doi.org/10.3390/cells10113215