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The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation
Basal cells (BCs) are stem/progenitor cells of the mucociliary airway epithelium, and their differentiation is orchestrated by the NOTCH signaling pathway. NOTCH3 receptor signaling regulates BC to club cell differentiation; however, the downstream responses that regulate this process are unknown. O...
Autores principales: | Bodas, Manish, Subramaniyan, Bharathiraja, Moore, Andrew R., Metcalf, Jordan P., Ocañas, Sarah R., Freeman, Willard M., Georgescu, Constantin, Wren, Jonathan D., Walters, Matthew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620267/ https://www.ncbi.nlm.nih.gov/pubmed/34831437 http://dx.doi.org/10.3390/cells10113215 |
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