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Roles for ADAM17 in TNF-R1 Mediated Cell Death and Survival in Human U937 and Jurkat Cells

Signaling via death receptor family members such as TNF-R1 mediates pleiotropic biological outcomes ranging from inflammation and proliferation to cell death. Pro-survival signaling is mediated via TNF-R1 complex I at the cellular plasma membrane. Cell death induction requires complex IIa/b or necro...

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Detalles Bibliográficos
Autores principales: Fritsch, Jürgen, Frankenheim, Julia, Marischen, Lothar, Vadasz, Timea, Troeger, Anja, Rose-John, Stefan, Schmidt-Arras, Dirk, Schneider-Brachert, Wulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620378/
https://www.ncbi.nlm.nih.gov/pubmed/34831323
http://dx.doi.org/10.3390/cells10113100