Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol

We studied the effect of several CDs on carvedilol’s solubility and chemical stability in various aqueous media. Our present results show that it is possible to achieve a carvedilol concentration of 5 mg/mL (12.3 mM) in the presence of 5 eq of γCD or RAMEB in an aqueous medium with an acceptable aci...

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Detalles Bibliográficos
Autores principales: Rigaud, Sébastien, Mathiron, David, Moufawad, Tarek, Landy, David, Djedaini-Pilard, Florence, Marçon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620534/
https://www.ncbi.nlm.nih.gov/pubmed/34834163
http://dx.doi.org/10.3390/pharmaceutics13111746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620534/
https://www.ncbi.nlm.nih.gov/pubmed/34834163
http://dx.doi.org/10.3390/pharmaceutics13111746

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