The Two Sweet Sides of Janus Lectin Drive Crosslinking of Liposomes to Cancer Cells and Material Uptake

A chimeric, bispecific Janus lectin has recently been engineered with different, rationally oriented recognition sites. It can bind simultaneously to sialylated and fucosylated glycoconjugates. Because of its multivalent architecture, this lectin reaches nanomolar avidities for sialic acid and fucos...

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Detalles Bibliográficos
Autores principales: Siukstaite, Lina, Rosato, Francesca, Mitrovic, Anna, Müller, Peter Fritz, Kraus, Katharina, Notova, Simona, Imberty, Anne, Römer, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620536/
https://www.ncbi.nlm.nih.gov/pubmed/34822576
http://dx.doi.org/10.3390/toxins13110792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620536/
https://www.ncbi.nlm.nih.gov/pubmed/34822576
http://dx.doi.org/10.3390/toxins13110792

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