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A Dual Anchoring Strategy for the Directed Evolution of Improved Artificial Transfer Hydrogenases Based on Carbonic Anhydrase

[Image: see text] Artificial metalloenzymes result from anchoring a metal cofactor within a host protein. Such hybrid catalysts combine the selectivity and specificity of enzymes with the versatility of (abiotic) transition metals to catalyze new-to-nature reactions in an evolvable scaffold. With th...

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Detalles Bibliográficos
Autores principales: Stein, Alina, Chen, Dongping, Igareta, Nico V., Cotelle, Yoann, Rebelein, Johannes G., Ward, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620556/
https://www.ncbi.nlm.nih.gov/pubmed/34849402
http://dx.doi.org/10.1021/acscentsci.1c00825