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Instrumental variable estimation for a time-varying treatment and a time-to-event outcome via structural nested cumulative failure time models
BACKGROUND: In many applications of instrumental variable (IV) methods, the treatments of interest are intrinsically time-varying and outcomes of interest are failure time outcomes. A common example is Mendelian randomization (MR), which uses genetic variants as proposed IVs. In this article, we pre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620657/ https://www.ncbi.nlm.nih.gov/pubmed/34823502 http://dx.doi.org/10.1186/s12874-021-01449-w |