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Instrumental variable estimation for a time-varying treatment and a time-to-event outcome via structural nested cumulative failure time models

BACKGROUND: In many applications of instrumental variable (IV) methods, the treatments of interest are intrinsically time-varying and outcomes of interest are failure time outcomes. A common example is Mendelian randomization (MR), which uses genetic variants as proposed IVs. In this article, we pre...

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Detalles Bibliográficos
Autores principales: Shi, Joy, Swanson, Sonja A., Kraft, Peter, Rosner, Bernard, De Vivo, Immaculata, Hernán, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620657/
https://www.ncbi.nlm.nih.gov/pubmed/34823502
http://dx.doi.org/10.1186/s12874-021-01449-w