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Effect of Selected Silyl Groups on the Anticancer Activity of 3,4-Dibromo-5-Hydroxy-Furan-2(5H)-One Derivatives

The pharmacological effects of carbon to silicon bioisosteric replacements have been widely explored in drug design and medicinal chemistry. Here, we present a systematic investigation of the impact of different silyl groups on the anticancer activity of mucobromic acid (MBA) bearing furan-2(5H)-one...

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Detalles Bibliográficos
Autores principales: Kitel, Radoslaw, Byczek-Wyrostek, Anna, Hopko, Katarzyna, Kasprzycka, Anna, Walczak, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620685/
https://www.ncbi.nlm.nih.gov/pubmed/34832861
http://dx.doi.org/10.3390/ph14111079