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Conditional CRISPR-Cas Genome Editing in Drosophila to Generate Intestinal Tumors

CRISPR-Cas has revolutionized genetics and extensive efforts have been made to enhance its editing efficiency by developing increasingly more elaborate tools. Here, we evaluate the CRISPR-Cas9 system in Drosophila melanogaster to assess its ability to induce stem cell-derived tumors in the intestine...

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Detalles Bibliográficos
Autores principales: Bahuguna, Shivohum, Redhai, Siamak, Zhou, Jun, Wang, Tianyu, Port, Fillip, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620722/
https://www.ncbi.nlm.nih.gov/pubmed/34831379
http://dx.doi.org/10.3390/cells10113156