Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model

Interferon gamma (IFNg) is a pleiotropic cytokine that can potentially reprogram the tumor microenvironment; however, the antitumor immunomodulatory properties of IFNg still need to be validated due to variable therapeutic outcomes in preclinical and clinical studies. We developed a replication-defi...

Descripción completa

Detalles Bibliográficos
Autores principales: Trofimova, Olga, Korotkaja, Ksenija, Skrastina, Dace, Jansons, Juris, Spunde, Karina, Isaguliants, Maria, Zajakina, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620866/
https://www.ncbi.nlm.nih.gov/pubmed/34835178
http://dx.doi.org/10.3390/vaccines9111247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620866/
https://www.ncbi.nlm.nih.gov/pubmed/34835178
http://dx.doi.org/10.3390/vaccines9111247

Ejemplares similares