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Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model
Interferon gamma (IFNg) is a pleiotropic cytokine that can potentially reprogram the tumor microenvironment; however, the antitumor immunomodulatory properties of IFNg still need to be validated due to variable therapeutic outcomes in preclinical and clinical studies. We developed a replication-defi...
Autores principales: | Trofimova, Olga, Korotkaja, Ksenija, Skrastina, Dace, Jansons, Juris, Spunde, Karina, Isaguliants, Maria, Zajakina, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620866/ https://www.ncbi.nlm.nih.gov/pubmed/34835178 http://dx.doi.org/10.3390/vaccines9111247 |
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