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The Potential Advantage of Targeting Both PD-L1/PD-L2/PD-1 and IL-10–IL-10R Pathways in Acute Myeloid Leukemia

Tumor cells promote the suppression of host anti-tumor type 1 T cell responses by various mechanisms, including the upregulation of surface inhibitory molecules such as programmed death ligand (PD-L)-1, and the production of immunosuppressive cytokines such as interleukin-10 (IL-10). There are over...

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Detalles Bibliográficos
Autores principales: Jimbu, Laura, Mesaros, Oana, Neaga, Alexandra, Nanut, Ana Maria, Tomuleasa, Ciprian, Dima, Delia, Bocsan, Corina, Zdrenghea, Mihnea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620891/
https://www.ncbi.nlm.nih.gov/pubmed/34832887
http://dx.doi.org/10.3390/ph14111105