Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors

Recently, combining histone deacetylase (HDAC) inhibitors with chemotherapeutic drugs or agents, in particular epidermal growth factor receptor (EGFR) inhibitors, is considered to be one of the most encouraging strategy to enhance the efficacy of the antineoplastic agents and decrease or avoid drug...

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Detalles Bibliográficos
Autores principales: Ibrahim, Tarek S., Malebari, Azizah M., Mohamed, Mamdouh F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620908/
https://www.ncbi.nlm.nih.gov/pubmed/34832959
http://dx.doi.org/10.3390/ph14111177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620908/
https://www.ncbi.nlm.nih.gov/pubmed/34832959
http://dx.doi.org/10.3390/ph14111177

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