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The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics

CYP2D6 and CYP2C19 enzymes are essential in the metabolism of antidepressants and antipsychotics. Genetic variation in these genes may increase risk of adverse drug reactions. Antidepressants and antipsychotics have previously been associated with risk of diabetes. We examined whether individual gen...

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Detalles Bibliográficos
Autores principales: Austin-Zimmerman, Isabelle, Wronska, Marta, Wang, Baihan, Irizar, Haritz, Thygesen, Johan H., Bhat, Anjali, Denaxas, Spiros, Fatemifar, Ghazaleh, Finan, Chris, Harju-Seppänen, Jasmine, Giannakopoulou, Olga, Kuchenbaecker, Karoline, Zartaloudi, Eirini, McQuillin, Andrew, Bramon, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620997/
https://www.ncbi.nlm.nih.gov/pubmed/34828364
http://dx.doi.org/10.3390/genes12111758